• It has been reported that expression of murine haspin

  2022-04-08

  

  It has been reported that expression of murine haspin is found only in post-meiotic spermatids and that overexpression of murine haspin in HEK-293 cells leads to reduced cell proliferation. Therefore, it was suggested that haspin functions to bring about Ergosterol mg arrest in haploid germ cells (T

• br Materials and methods br Results br Discussions

  2022-04-08

  

  Materials and methods Results Discussions The treated tannery effluent (both MF and MF+RO treated) was free from most of the organic and inorganic loadings as reflected from the values of COD, BOD, total kjeldahl nitrogen (TKN) and sulfides etc. Toxicity study of the effluent (both treated

• br Conclusion Interactions between neurons and

  2022-04-08

  

  Conclusion Interactions between neurons and astrocytes depend on the spatial configuration of their contacts. Therefore, changes of astrocyte morphology may impact various physiological mechanisms ranging from glutamate uptake and potassium homeostasis to modulation of synaptic transmission and p

• We show that pharmacological inactivation of

  2022-04-08

  

  We show that pharmacological inactivation of GSTP1 over a sustained period does not show any observable toxicity, and not only prevents breast tumor growth but even slows established breast tumor growth in mice. A highly potent GSTP1 inhibitor, ezatiostat (developed by Telik Inc.) has passed phase I

• br Conclusion GST expression was detected in the Hemicornea

  2022-04-08

  

  Conclusion GST expression was detected in the Hemicornea construct and the commonly used animal cornea models at both the protein and functional levels. The results are summarized in Table 1. However, the construct exhibited lower levels of activity of GST, a marker of phase II enzymatic activity

• br GSNOR regulates SA synthesis

  2022-04-08

  

  GSNOR1 regulates SA synthesis and SA signalling The phenolic metabolite salicylic Epothilone B (SA) is a powerful immune activator in plants. Moreover, mutations that disable SA biosynthesis or transgenes that result in its depletion compromise both resistance (R) gene-mediated and basal resista

• In order to investigate whether this off target

  2022-04-08

  

  In order to investigate whether this off-target activity was related to a particular structural feature of this 1,4-DPCA receptor or was characteristic of the series, compounds , and were selected as being matched pairs with compound but with structural variation in terms of the R, R and R group

• Caspase-9 Colorimetric Assay Kit During the tests in vitro S

  2022-04-08

  

  During the tests in vitro, SHP289-04 showed the beneficial effect on both two important aspects. In human liver carcinoma cell line HepG2, it was found to improve glucose consumption significantly. Otherwise, in pancreas cell line NIT1, it could only promote insulin secretion significantly at high g

• The role of the ER EK variant which is

  2022-04-08

  

  The role of the ER22/23EK variant which is associated with relative resistance to GC, as shown by a reduction of transactivating capacity in vitro and less suppression of gssg levels after 1mg DST in vivo. Relative GC resistance associated with the ER22/23EK polymorphism might protect from the deve

• br Phylogenetic analysis of vertebrate

  2022-04-08

  

  Phylogenetic analysis of vertebrate receptors for peptides similar to glucagon Genes for receptors for peptides similar to glucagon and other secretin-like hormones have been identified in a number of vertebrate species (Sivarajah et al., 2001, Chow et al., 2004, Irwin and Wong, 2005, Cardoso et

• It was previously proposed that glucagon acts in the liver

  2022-04-08

  

  It was previously proposed that glucagon acts in the liver, in which a signal is produced and relayed to the Glucose Uptake Fluorometric Assay Kit sale via vagal nerves [8], [36], [37]. The concept that the liver is the primary target site was supported by the studies reporting that the glucagon re

• br Ghrelin Ghrelin was purified from rat stomach

  2022-04-08

  

  Ghrelin Ghrelin was purified from rat stomach about twenty years ago as a 28-amino Cholic acid receptor octanoylated peptide and shown to be the endogenous ligand of the growth hormone (GH) secretagogue receptor (now termed GHSR1a, Howard et al., 1996, Kojima et al., 1999). GHSR1a is a 7-transme

• There are multiple docking platforms

  2022-04-07

  

  There are multiple docking platforms suitable for use with nucleic Penciclovir receptors. These include: DOCK v4-6 (UCSF) [[68], [69], [70]], AutoDock (Scripps) [71], AutoDock Vina (Scripps) [72], GOLD (Cambridge Crystallographic Data Centre) [73], Surflex-DOCK (BioPharmics) [74], Glide (Schrӧdinge

• FPR activation stimulates multiple signal transduction pathw

  2022-04-07

  

  FPR1 activation stimulates multiple signal transduction pathways responsible for various neutrophil functions, such as adhesion, chemotaxis, phagocytosis, AMG-517 synthesis of secretory granules, and superoxide anion radical (O2) production, which contribute to the physiological inflammatory respon

• TTNPB Accordingly and in animal models a high fat diet rich

  2022-04-07

  

  Accordingly and in animal models, a high-fat diet rich in CO (CO-HFD) impeded ventricular function and induced cardiac cell death and remodeling, at least, by down-regulating cell antioxidant defense systems and induction of oxidative stress [28], [29], [30], [31]. Interestingly, long chain fatty ac

15720 records 440/1048 page Previous Next First page 上5页 436437438439440 下5页 Last page