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In conclusion over expression of Stokesia epoxygenase
2020-06-05
In conclusion, over-expression of Stokesia epoxygenase (SlEPX) in soybean seeds led to some unusual seed phenotypes. These effects can be overcome by coexpression of Vernonia DGATs (VgDGAT1 & 2). The DGATs can specifically transfer vernolic Cetrorelix into TAG, largely reducing vernolic acid levels
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Predictions of enzyme topology for DGAT
2020-06-05
Predictions of enzyme topology for DGAT2 are more difficult since the DGAT2 polypeptide sequences are more diverse across species than those of DGAT1. The length and function of the hydrophilic N-terminus preceding the first hydrophobic segment varies with species – for example, segments in fungi ar
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As temperatures increase rates of spontaneous
2020-06-05
As temperatures increase, rates of spontaneous deamination also increase such that hyperthermophilic organisms must have efficient mechanisms for dealing with this potential hazard.8., 9. The hyperthermophile Methanococcus jannaschii has both a dCTP deaminase (encoded by the gene at locus MJ0430) an
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Functionally all members of the IL family
2020-06-05
Functionally, all members of the IL-12 family have been annotated along major inflammatory signaling axes but their roles have often weighed on opposing sides of the immunological balance. For instance, IL-12 and IL-23 are classified as pro-inflammatory cytokines [10] as opposed to the rather protec
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Some studies have demonstrated that BMSCs
2020-06-05
Some studies have demonstrated that BMSCs can provide several trophic and growth factors that play important roles in cell survival, angiogenesis, and BMSC differentiation, but not cell replacement (Peled et al., 1999, Shen et al., 2007, Ji et al., 2004). This paracrine effect of BMSCs is a potentia
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In this study new and more extended tables of parameters
2020-06-05
In this study, new and more extended tables of parameters were estimated for pure fluids and binary mixtures that are relevant to biodiesel systems. Also, calculations for glyceride systems will be shown, which is a topic not investigated before with the CPA model. As before [21], [22], [23], [24],
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System Analysis and Modeling In
2020-06-05
System Analysis and Modeling - In this work, a three-level hierarchical modeling – composed by combinatorial and state-space models – is used: (1) First, failure rates () of TMS servers subsystem units are estimated through continuous Markov chains; (2) Then, the single server TBB failure rate () i
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Similarly LTD concentration dependently enhanced AQP express
2020-06-04
Similarly, LTD4 concentration-dependently enhanced AQP4 expression in astrocytes (Fig. 3). The LTD4-enhanced AQP4 expression was not affected by pranlukast but inhibited by Bay u9773, a non-selective CysLT1/CysLT2 receptor antagonist [33]. Because no selective CysLT2 receptor antagonists are current
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The N B method has the overall advantage that
2020-06-04
The N&B method has the overall advantage that it is not restricted to certain dyes specific for energy transfer [55], and is also able to detect higher order receptor PPADS tetrasodium salt on the focal point in living cells. Conclusion The N&B method has shown to be a powerful tool to locate a
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Endothelial dysfunction has been associated with
2020-06-04
Endothelial dysfunction has been associated with most of the established cardiovascular risk factors, such as hypercholesterolemia, hypertension, smoking, diabetes mellitus, a positive history of premature CAD and elevated cAMPS-Sp, triethylammonium salt homocysteine 4, 26, 27. Endothelial dysfunc
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br Disclosure statement br Acknowledgment This work was supp
2020-06-04
Disclosure statement Acknowledgment This work was supported by the National Natural Science Foundation of China (81270704, 81330018). Background Over-expression of cyclooxygenase-2 (COX-2) is common in many malignancies including non-small cell lung cancer (NSCLC) and is associated with po
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The Liver X Receptor and LXRs NR H
2020-06-04
The Liver X Receptor-α and -β (LXRs, NR1H3 and NR1H2, respectively) are members of the nuclear receptor superfamily that play a central role in controlling cholesterol homeostasis [9], [10]. In macrophages, LXRs can decrease the cellular sterol burden by inducing expression of the cholesterol efflux
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br Methodology To simulate chip
2020-06-04
Methodology To simulate chip flow trajectory, the force and torque acting on the chips in high pressure coolant are computed based on the control volume method [6]. During the setup, a typical gun drill chip and gun drill bit are imported into ANSYS CFX 14.0 and prescribed as stationary solids. T
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An important question is to what extent any
2020-06-04
An important question is to what extent any differences in radioligand characteristics may have contributed to discrepancies between studies. Two studies on schizophrenia addressed this question directly by using [11C]SCH 23390 and [11C]NCC 112 in the same individuals, not finding any differences b
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Molecular modelling studies were performed on the hDHFR inhi
2020-06-04
Molecular modelling studies were performed on the hDHFR inhibitors identified (1, 11, 13, 14, 16, 25 and 32) to explore the structural basis of the interaction between the mentioned compounds and the human enzyme. The docking studies were performed using the X-ray crystallographic structure of the h
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